Predictive Power Estimation Algorithm (PPEA)--a new algorithm to reduce overfitting for genomic biomarker discovery.
Toxicogenomics promises to aid in predicting adverse effects, understanding the mechanisms of drug action or toxicity, and uncovering unexpected or secondary pharmacology.However, modeling adverse effects using high dimensional and high 2006 scion xa catalytic converter noise genomic data is prone to over-fitting.Models constructed from such data s